Malaria

July 21st, 2010 by admin

Malaria is a vector-borne infectious disease caused by a protozoan parasite of the genus Plasmodium, which is transmitted from human to human by the bite of infected female Anopheles mosquitoes. There are four identified species of Plasmodium, namely, P. vivax, P. falciparum, P. ovale and P. malariae: P.falciparum being the most fatal one. The life cycle of Plasmodium inside human body begins with a series of asexual divisions in liver and then red blood cells. The sporozoites, injected by the infected female Anopheles mosquito, are carried to the liver, where they undergo asexual forms known as exoerythrocytic schizogony to form merozoites. When these infected liver cells burst, merozoites are released into the blood, where they invade red blood cells. After invading the erythrocyte, merozoite de-differentiates into a round trophozoite form. The young trophozoite or the ring stage grows substantially to form schizont. Finally, it undergoes 4-5 rounds of binary divisions during the schizont stage, producing 8-36 new merozoites that burst from the host cell to invade new erythrocytes, beginning another round of infection. This phase of the infection (erythrocytic schizogony) is responsible for malaria pathogenesis. The parasites multiply within red blood cells, causing symptoms that include symptoms of anemia (light-headedness, shortness of breath, tachycardia, etc.), as well as other general symptoms such as fever, chills, nausea, flu-like illness, and, in severe cases, coma, and death. This animation emphasizes on the life cycle of Plasmodium inside human host.

Duration : 0:2:51


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Posted in anemia symptoms

20 Responses

  1. sharksor

    omg i have so many …
    omg i have so many mosquito bited i hope i dont hsve it :O

  2. hombrelobo28

    Muy asombroso, que …
    Muy asombroso, que material tan didactico. Gracias por compartirlo

  3. Proteinlounge

    Ya it is, if not …
    Ya it is, if not treated properly, specially brain malaria, caused by P.falciparum.

  4. mcfly626

    is this a deadly …
    is this a deadly disease ?

  5. albrestevez

    merci.. it really …
    merci.. it really helps to memorize bcus makes everythin more clrear =D
    Gracias amigo!!

  6. HARSHA43333333333333

    FINE
    FINE

  7. 01Rell

    wow….love it. …
    wow….love it. wish there waz sound…but love it

  8. msbabe08

    great vid!
    great vid!

  9. helpthekids89

    Why isn’t there any …
    Why isn’t there any sound?

  10. Scorptarius

    Awesome video!
    Awesome video!

  11. Proteinlounge

    thanks for the …
    thanks for the comments.

  12. axixarro

    nice video… …
    nice video… simple and illustrative ;)

  13. MrBeaste

    You can grow new …
    You can grow new liver cells I believe

  14. lolqqqlol

    will what i want is …
    will what i want is simply Explanation of the plasmodium’s Life cycle inside the vector and the vertebrate host ( in this case humans i guess ) i do not need articles or something sense i have to be the one explaining it so i need something that is simple not too long but important … i know i am asking for a lot but is that possible i have about.. 2 or 2 and a 1/2 weeks till the Deadline .

  15. Proteinlounge

    ofcourse. just you …
    ofcourse. just you give your mail id and clarify what sort of information you want..i mean you need articles on plasmodium or anything else. i will help you in whatever way i can?

  16. jennyEvansmd

    Amazing video..nice …
    Amazing video..nice visuals and good representation. Haven’t seen anything like this on malaria.

  17. lolqqqlol

    and by Plasmodium i …
    and by Plasmodium i mean only the kinds that give human malaria

  18. lolqqqlol

    oh must have been …
    oh must have been thinking of something else.. i am taking high school biology right now so i need information to write a report on Plasmodium do u have anything else on the subject ?

  19. Proteinlounge

    The female mosquito …
    The female mosquito has a specialised apparatus to penetrate the skin of its victim. At the end of the slender proboscis, there are two pairs of cutting stylets that slide against one another to slice through the skin. Once through the skin, the mosquito’s proboscis begins probing for a tiny blood vessel. If it does not strike one on the first try, the mosquito will pull back slightly and try again at another angle through the same hole in the skin, so need no wound.

  20. lolqqqlol

    wait i thought …
    wait i thought Anopheles go to open wounds to feed.. dont they ??

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